![]() ![]() This score is a prospectively derived, validated means of estimating 1-year mortality of STEMI at hospital discharge and can serve as a clinically useful tool. In the validation database, the C-statistic was 0.81, with a NRI of 0.35 (P=0.01). The C-statistic produced by the dynamic score in the derivation database was 0.76, with a net reclassification improvement (NRI) of 0.33 (P<0.0001) from the inclusion of dynamic events to the original TIMI risk score. The dynamic score included the development of in-hospital MI, arrhythmia, major bleed, stroke, congestive heart failure, recurrent ischemia, and renal failure. Each variable was assigned an integer value based on the odds ratio, and the final score was the sum of these values. Variables with P<0.05 were incorporated into a full multivariable Cox model to assess the risk of death at 1 year. Each variable was tested individually in a univariate Cox proportional hazards regression. New variables were major clinical events occurring during the index hospitalization. Baseline variables were from the original TIMI risk score for STEMI. The dynamic TIMI risk score for STEMI was derived in ExTRACT-TIMI 25 and validated in TRITON-TIMI 38. A dynamic risk score provides an initial risk stratification and reassessment at discharge. The total possible score is 14.Although there are multiple methods of risk stratification for ST-elevation myocardial infarction (STEMI), this study presents a prospectively validated method for reclassification of patients based on in-hospital events. The TIMI risk score for TIMI is calculated by adding the numbers assigned to the different criteria shown below. TIMI Risk Score for STEMI Calculation of TIMI Risk Score for STEMI Risk of the all-cause mortality, myocardial infarction, or severe recurrent ischemia through 14 days The risk at 14 days of either all-cause death, new or recurrent MI, or severe recurrent ischemia requiring urgent revascularization is as follows: Score Interpretation of TIMI Risk Score for Unstable Angina Ischemia (at least two anginal events in previous 24 hours)Ĭoronary artery stenosis (prior stenosis of 50% or more) Risk factors (at least three for coronary artery disease) TIMI Risk Score Calculator for Unstable Angina or NSTEMI Risk FactorĬardiac enzymes (raised serum cardiac markers)ĮKG ( ST segment depression at presentation) The TIMI risk score for unstable angina ( UA) or Non ST Segment Elevation MI ( NSTEMI) was derived in the test cohort by selection of independent prognostic variables using multivariate logistic regression, assignment of value of 1 when a factor was present and 0 when it was absent, and summing the number of factors present to categorize patients into a level of risk. ![]() TIMI Risk Score for Unstable Angina Calculation of TIMI Risk Score for Unstable Angina or Non ST Segment Elevation MI (NSTEMI) There are separate scores for patients with unstable angina or non ST elevation myocardial infarction and ST elevation myocardial infarction. ![]() The TIMI Risk Score provides prognostic information regarding the risk of future adverse clinical outcomes among patients with acute coronary syndromes. Associate Editor(s)-in-Chief: Rim Halaby, M.D. Risk calculators and risk factors for TIMI risk scoreĬauses & Risk Factors for TIMI risk scoreĮditor-In-Chief: C. ![]() US National Guidelines Clearinghouse on TIMI risk scoreĭirections to Hospitals Treating TIMI risk score Ongoing Trials on TIMI risk score at Clinical Ĭlinical Trials on TIMI risk score at Google Articles on TIMI risk score in N Eng J Med, Lancet, BMJĬochrane Collaboration on TIMI risk score ![]()
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